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. 2017 Nov 9;18(11):2378. doi: 10.3390/ijms18112378

Figure 1.

Figure 1

Contribution of the endothelium to cumulative applications of uridine adenosine tetraphosphate (Up4A) in the aortas of LETO and OLETF rats under basal conditions or after being precontracted with phenylephrine (PE). Concentration-response curves for Up4A in endothelium-intact (+EC) and -denuded (−EC) aortas under basal conditions (A) or precontracted with PE (10−6 mol/L). (B) The points show the means ± standard errors as percentages of the contraction normalized by high K+ (80 mmol/L) (A) or as percentages of the relaxation of the contraction induced by PE (10−6 mol/L) (B). n = 5–6. * p < 0.05, +EC LETO vs. +EC OLETF aortas. # p < 0.05, +EC LETO vs. −EC LETO aortas. † p < 0.05, +EC OLETF vs. −EC OLETF. ‡ p < 0.05, −EC LETO vs. −EC OLETF aortas. LETO, Long-Evans Tokushima Otsuka rats; OLETF, Otsuka Long-Evans Tokushima Fatty rats.