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. 2017 Nov 9;18(11):2378. doi: 10.3390/ijms18112378

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Release of the prostanoids prostaglandin (PG)F_2α (A), thromboxane (Tx)B₂ (a stable metabolite of TxA₂) (B), PGE₂ (C), and 6-keto-PGF_1α (a stable metabolite of PGI₂) (D), evoked by uridine adenosine tetraphosphate (Up₄A; 3 × 10⁻⁵ mol/L) or vehicle (water) in aortic rings obtained from LETO (n = 7) and OLETF (n = 7) rats. The y-axis shows amounts of prostanoids expressed as pg/mg wet weight of aortic ring. Each column represents means ± standard error. * p < 0.05 vs. Up₄A LETO. LETO, Long-Evans Tokushima Otsuka rats; OLETF, Otsuka Long-Evans Tokushima Fatty rats; n.s., not significant.

Release of the prostanoids prostaglandin (PG)F_2α (A), thromboxane (Tx)B₂ (a stable metabolite of TxA₂) (B), PGE₂ (C), and 6-keto-PGF_1α (a stable metabolite of PGI₂) (D), evoked by uridine adenosine tetraphosphate (Up₄A; 3 × 10⁻⁵ mol/L) or vehicle (water) in aortic rings obtained from LETO (n = 7) and OLETF (n = 7) rats. The y-axis shows amounts of prostanoids expressed as pg/mg wet weight of aortic ring. Each column represents means ± standard error. * p < 0.05 vs. Up₄A LETO. LETO, Long-Evans Tokushima Otsuka rats; OLETF, Otsuka Long-Evans Tokushima Fatty rats; n.s., not significant.