Table 1.
Relative fold change and functions of DETS in 3-month-old mice.
| Gene Name | Functions | Fold Change |
|---|---|---|
| CASP9 | Apoptosis | −0.35 |
| MAPK9 | Apoptosis | −0.39 |
| NR4A2 | Apoptosis, Dopaminergic Signaling | −0.34 |
| CASP3 | Apoptosis, Mitochondrial | −0.44 |
| OPA1 | Apoptosis, Mitochondrial | −0.29 |
| CDH8 | Cell Adhesion Molecules | −0.35 |
| FN1 | Cell Adhesion Molecules | −0.38 |
| NFASC | Cell Adhesion Molecules | −0.33 |
| NRXN3 | Cell Adhesion Molecules | −0.35 |
| TPBG | Cell Adhesion Molecules | −0.16 |
| PTEN | Cell Adhesion Molecules, Apoptosis, Mitochondrial | −1.44 |
| DRD2 | Dopaminergic Signaling | −0.35 |
| SLC6A3 | Dopaminergic Signaling | −0.34 |
| GABBR2 | GABAergic Signaling | −0.13 |
| ATP2B2 | Ion Transport | −0.39 |
| CXXC1 | Ion Transport | −0.41 |
| EGLN1 | Ion Transport | −0.40 |
| GRIA3 | Ion Transport | −0.40 |
| HTR2A | Ion Transport | −0.36 |
| KCNJ6 | Ion Transport | −0.26 |
| NSF | Ion Transport | −0.29 |
| SLIT1 | Ion Transport | −0.34 |
| SRSF7 | Ion Transport | −0.41 |
| ALDH1A1 | Other Parkinson’s Disease Genes | −0.37 |
| BASP1 | Other Parkinson’s Disease Genes | −0.21 |
| CHGB | Other Parkinson’s Disease Genes | −0.40 |
| NCOA1 | Other Parkinson’s Disease Genes | −0.40 |
| RTN1 | Other Parkinson’s Disease Genes | −0.34 |
| STUB1 | Parkin Complex, Ubiquitination | −0.32 |
| ATXN2 | Parkin Substrate | −0.32 |
| ATXN3 | Parkin Substrate | −0.33 |
| GPR37 | Parkin Substrate | −0.30 |
| SYT11 | Parkin Substrate, Synaptic Vesicles | −0.35 |
| SV2B | Synaptic Vesicles | −0.22 |
| SYNGR3 | Synaptic Vesicles | −0.22 |
| SYT1 | Synaptic Vesicles | −0.32 |
| SEPT5 | Synaptic Vesicles, Dopaminergic Signaling | −0.23 |
| UBC | Ubiquitination | +0.49 |
| USP34 | Ubiquitination | −0.36 |
| LRRK2 | Ubiquitination, Mitochondrial, Synaptic Vesicles | −0.39 |
| PARK2 | Ubiquitination, Mitochondrial, Dopaminergic Signaling | −0.18 |
| PINK1 | Ubiquitination, Mitochondrial, Dopaminergic Signaling | −0.23 |