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. 2017 Nov 21;18(11):2480. doi: 10.3390/ijms18112480

Figure 5.

Figure 5

Aco2 protein expression and activity in peripheral blood mononuclear cells (PBMC) of HD patients and pre-symptomatic HD mutation (PreHD) carriers. (A) PBMC Aco2 expression levels, analyzed by western blot, in HD patients and PreHD carriers were compared with the control group (NC). The expression levels of Aco2 were normalized by Gapdh. M, marker for protein molecular weight. (B) Aco2 activities of PBMC in PreHD carriers (n = 6) and HD patients (n = 19) were compared with the controls (n = 25). HD1 group (n = 7): more severe disease group. HD2 group (n = 12): milder disease group. Data are presented as means ± SE (standard error). * p < 0.05; *** p < 0.001, Mann–Whitney–U or Kruskal–Wallis test, where appropriate.