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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Arch Toxicol. 2017 May 17;91(7):2655–2661. doi: 10.1007/s00204-017-1988-8

Fig. 2.

Fig. 2

SMZ (top), ABP (middle) and PABA (bottom) N-acetyltransferase catalytic activities in vitro in human hepatocyte lysates of heterozygous genotypes. Each bar illustrates mean ± SEM for NAT2*4/*5B (n=64) and NAT2*4/*6A (n=30) individual human hepatocyte samples. Differences in N-acetyltransferase catalytic activity between the heterozygous NAT2*4/*5B and NAT2*4/*6A genotypes were not significant towards SMZ (p=0.5851), ABP (p=0.9485) or PABA (p=0.0821) respectively for SMZ, ABP or PABA. Portions of this data were published previously (Hein and Doll, 2012) where the statistical analysis did not focus on these two NAT2 genotypes.