Table 4.
Percentage of proliferated CD4+ T cells after different DC stimulations
| Group | Proliferated (%) Raw values
|
Proliferated (%) imDC (%) Proliferated×100%
|
Proliferated (%)/mDC (%) Proliferated×100%
|
||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| #1 | #2 | #3 | #1 | #2 | #3 | Average | SD | #1 | #2 | #3 | Average | SD | |
| imDC | 65.3% | 72.4% | 58.0% | 100.0% | 100.0% | 100.0% | 100.0% | – | |||||
| imDC-AFP | 67.3% | 73.1% | 55.1% | 103.1% | 101.0% | 95.0% | 99.7% | 4.2% | |||||
| mDC | 78.5% | 80.8% | 65.5% | 120.2% | 111.6% | 112.9% | 114.9% | 4.6% | 100.0% | 100.0% | 100.0% | 100.0% | – |
| mDC-AFP | 72.6% | 76.9% | 60.4% | 111.2% | 106.2% | 104.1% | 107.2% | 3.6% | 92.5% | 95.2% | 92.2% | 93.3% | 1.6% |
|
| |||||||||||||
| p-value | imDC vs mDC-AFP | 0.0264* | mDC vs mDC-AFP | 0.0021* | |||||||||
Notes: Left column: raw percentage values of proliferated CD4+ T cells taken directly from the histogram. Middle column: proliferated CD4+ T cells’ raw values from the left column, normalized with imDC group taken as the control, while the treated groups were compared relative to imDC in percentage. Right column: proliferated CD4+ T cells’ raw values from the left column, normalized with non-treated mDC group taken as the control, while mDC-AFP was compared relative to non-treated mDC in percentage, done particularly to show similar proliferation decrease due to DC AFP prior treatment in all three biological replicates.
p<0.05.
Abbreviations: DC, dendritic cell; imDC, immature DC; imDC-AFP, alpha-fetoprotein-treated imDC; mDC, mature DC; mDC-AFP, alpha-fetoprotein-treated mDC.