Table 2.
Characterization of liposomes formulations with Ghrl and lipid concentrations of 1 mg/mL and 10 mg/mL, respectively
| Formulations |
Z-average (nm)(PDI)
|
ζ-Potential (mV)
|
EE (%)
|
||
|---|---|---|---|---|---|
| Free | Ghrl | Free | Ghrl | Ghrl | |
| Anionic liposomes | 130.2±1.3 (0.098) | 146.9±2.7 (0.105) | −14.0±0.7 | −0.3±1.2 | 56.1±7.8 |
| Neutral liposomes | 143±2.2 (0.105) | 152.9±4.8 (0.094) | +0.5±0.4 | +4.1±1.4 | 21.3±4.1 |
| Cationic liposomes | 137.3±3.6 (0.082) | 151±3.9 (0.062) | +13.5±1.5 | +18.9±3.1 | 9.8±3.7 |
Note: Data presented as means ± SD (n=3).
Abbreviations: Ghrl, ghrelin; PDI, polydispersity index; EE, encapsulation efficiency.