Table 2.
Univariate and multivariate analyses of factors associated with overall survival
| Variables | Univariate analysis
|
P-value^ | Multivariate analysis
|
P-value^^ | ||
|---|---|---|---|---|---|---|
| HR | 95% CI | HR | 95% CI | |||
| miR-211 | 3.245 | 1.213–8.685 | 0.019 | 3.222 | 1.204–8.624 | 0.020 |
| Age | 2.224 | 0.677–7.299 | 0.188 | – | – | – |
| Gender | 2.430 | 0.779–7.580 | 0.123 | – | – | – |
| Tobacco smoking status | 2.671 | 1.028–6.941 | 0.044 | 2.999 | 1.085–8.290 | 0.034 |
| Tumor size (cm) | 3.301 | 1.096–8.381 | 0.033 | 2.975 | 1.076–8.226 | 0.036 |
| Alcohol drinking status | 2.630 | 0.882–7.844 | 0.083 | – | – | – |
| Tumor stage | 3.183 | 1.189–8.519 | 0.021 | 3.028 | 1.095–8.373 | 0.020 |
Notes:
^
Log-rank test.
^^
Cox regression model. – indicates not enrolled in the multivariate analysis.
Abbreviations: CI, confidence interval; HR, hazard ratio; miR-211, microRNA-211.