Table 5.

Dysregulated miRNA in peripheral blood mononuclear cells from severe compared with mild AATD emphysema patients

miRNA ID	logFC	P-value
Upregulated
hsa-miR-708-5p	2.46	0.009
hsa-miR-4440	2.42	0.007
hsa-miR-193b-3p	2.01	0.036
hsa-miR-3934-5p	1.79	0.030
hsa-miR-7846-3p	1.69	0.003
hsa-miR-873-5p	1.57	0.008
hsa-miR-27a-5p	1.56	0.003
hsa-miR-3064-3p	1.53	0.018
hsa-miR-146b-3p	1.50	0.003
hsa-miR-193b-5p	1.38	0.009
hsa-miR-873-3p	1.37	0.035
hsa-miR-146b-5p	1.31	0.006
hsa-miR-2278	1.31	0.021
hsa-miR-1255a	1.28	0.005
hsa-miR-1225-5p	1.24	0.035
hsa-miR-135a-3p	1.18	0.004
hsa-miR-4723-5p	1.16	0.037
hsa-miR-874-3p	1.11	0.008
hsa-miR-365a-5p	1.11	0.003
hsa-miR-29b-1-5p	1.10	0.003
Downregulated
hsa-miR-543	−1.00	0.018
hsa-miR-139-3p	−1.00	0.013
hsa-miR-485-3p	−1.02	0.049
hsa-miR-335-5p	−1.01	0.047
hsa-miR-139-5p	−1.01	0.040
hsa-miR-486-3p	−1.05	0.049
hsa-miR-185-3p	−1.12	0.020
hsa-miR-328-3p	−1.20	0.025

Note: Table 5 shows different miRNAs using P-value <0.05 and logFC >±1.

Abbreviations: AATD, alpha1-antitrypsin deficiency; logFC, fold change logarithm; miRNA, microRNA.