[Table/Fig-1]:
S. No | Genotypes/Alleles | Controls (n=164) | Patients (n=184) | OR* (95%CI) p-value |
---|---|---|---|---|
miRNA 146a | ||||
1. | GG | 84 (51.21%) | 81 (44.02%) | Reference |
2. | GC | 72 (43.90%) | 85 (46.19%) | 1.218 (0.786-1.889)0.378 |
3. | CC | 8 (4.87%) | 18 (9.78%) | 2.391 (0.982-5.818)0.055 |
G | 240 (73.17 %) | 247 (67.11%) | Reference | |
C | 88 (26.82%) | 121 (32.88%) | 1.341 (0.966-1.861)0.079 | |
miRNA 196a2 | ||||
1. | CC | 21 (12.80%) | 20 (10.86%) | Reference |
2. | CT | 81 (43.90%) | 93 (50.54%) | 1.233 (0.622-2.444)0.548 |
3. | TT | 62 (37.80%) | 71 (38.58%) | 1.234 (0.610-2.495)0.588 |
C | 123 (37.5%) | 133 (36.14%) | Reference | |
T | 205 (62.5%) | 235 (63.85%) | 1.070 (0.785-1.457)0.669 | |
miRNA 499 | ||||
1. | TT | 54 (32.9%) | 26 (14.1%) | Reference |
2. | CT | 76 (46.34%) | 78 (42.39%) | 2.136 (1.214-3.757)0.008 |
3. | CC | 34 (20.73%) | 80 (43.47%) | 4.801 (2.589-8.904)0.001 |
C | 144 (43.9%) | 238 (64.6%) | Reference | |
T | 184 (56.0%) | 130 (35.3%) | 2.307 (1.619-3.131)0.001 |
*OR = odds ratio