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. 2017 Sep 1;11(9):GC01–GC04. doi: 10.7860/JCDR/2017/25361.10543

[Table/Fig-1]:

Distribution of hsa-miRNA gene polymorphisms.

S. No Genotypes/Alleles Controls (n=164) Patients (n=184) OR* (95%CI) p-value
miRNA 146a
1. GG 84 (51.21%) 81 (44.02%) Reference
2. GC 72 (43.90%) 85 (46.19%) 1.218 (0.786-1.889)0.378
3. CC 8 (4.87%) 18 (9.78%) 2.391 (0.982-5.818)0.055
G 240 (73.17 %) 247 (67.11%) Reference
C 88 (26.82%) 121 (32.88%) 1.341 (0.966-1.861)0.079
miRNA 196a2
1. CC 21 (12.80%) 20 (10.86%) Reference
2. CT 81 (43.90%) 93 (50.54%) 1.233 (0.622-2.444)0.548
3. TT 62 (37.80%) 71 (38.58%) 1.234 (0.610-2.495)0.588
C 123 (37.5%) 133 (36.14%) Reference
T 205 (62.5%) 235 (63.85%) 1.070 (0.785-1.457)0.669
miRNA 499
1. TT 54 (32.9%) 26 (14.1%) Reference
2. CT 76 (46.34%) 78 (42.39%) 2.136 (1.214-3.757)0.008
3. CC 34 (20.73%) 80 (43.47%) 4.801 (2.589-8.904)0.001
C 144 (43.9%) 238 (64.6%) Reference
T 184 (56.0%) 130 (35.3%) 2.307 (1.619-3.131)0.001

*OR = odds ratio