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. Author manuscript; available in PMC: 2017 Dec 4.
Published in final edited form as: JAMA. 2017 Feb 7;317(5):507–515. doi: 10.1001/jama.2016.21035

Figure 2. Prevalence of Prediabetes and Diabetes by Sickle Cell Trait Status Among Participants Not Taking Diabetes Medications and With No Prior Diagnosis of Diabetes.

Figure 2

Fasting glucose and hemoglobin A1c analyses included 7499 total observations (6877 observations from participants without sickle cell trait [SCT] and 572 from participants with it). Analyses for 2-hour glucose concentrations were only available from CARDIA participants and included 1869 total observations (1752 observations from participants without SCT and 117 from participants with SCT). For the definition of prediabetes and diabetes by glucose measures, see the Methods section. The prevalence of prediabetes and diabetes by fasting glucose and 2-hour glucose concentration was similar in those with and without SCT (P > .10 for all comparisons). However, the prevalence of prediabetes and diabetes as defined by hemoglobin A1c was significantly higher among participants with vs without SCT (P < .001 for both). Error bars indicate 95% CIs.