Figure 1.

Exogenous H₂S ameliorated cardiac dysfunction in L-NAME-induced hypertensive rats. (a–d) Hemodynamic parameter analysis. (e) Changes of systolic blood pressure at the beginning and after five weeks of the experimental period. (f) H₂S levels in plasma. (g) CSE activity in heart tissues. Results are means ± SEM. ^**P < 0.01 vs. Control group; ^##P < 0.01 vs. L-NAME group. A P of <0.05 was considered significant. CSE: cystathionine-γ-lyase; LVDP: left ventricular developing pressure; HR: heart rate; ±LV dP/dt_max: maximal positive and negative velocity of left ventricular pressure. (A color version of this figure is available in the online journal.)