Table 5.

The result of gene set enrichment analysis of 22 genes differentially expressed after chemotherapy.

ID	Description	setSize	enrichmentScore	P-adjust
1650814	Collagen biosynthesis and modifying enzymes	9	0.61	0.09
1474290	Collagen formation	10	0.54	0.09
168273	Influenza viral RNA transcription and replication	22	0.52	0.09
156842	Eukaryotic translation elongation	21	0.56	0.09
216083	Integrin cell surface interactions	8	0.61	0.09
1799339	SRP-dependent cotranslational protein targeting to membrane	21	0.56	0.09
1442490	Collagen degredation	9	0.76	0.09

Note: We used hypergeometric model to assess whether the number of selected genes associated with the reactome pathway is larger than expected. We listed here the most significant pathways with P-adjusted <0.1 (after correction for multiple testing). The enrichment score reflects the degree to which a gene set is overrepresented at the extremes (top or bottom) of the entire ranked list.