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. 2017 Nov 22;11(1):56–64. doi: 10.1016/j.tranon.2017.10.011

Figure 4.

Figure 4

One responder case: invasive ductal carcinoma in a 48-year-old woman. (A, B) US images show a pre- and posttreatment lesion with hypoechoic, irregular shape and indistinct margins, with US measuring pre-size of 3.6 cm and post-size 0.7 cm in diameter. It was a pathologically complete response with Miller-Payne grade 5; therefore, ΔSmean (tL) was 100%. (C, D) Pre- and posttreatment reconstructed optical absorption maps show that the lesion was resolved in slices from 1 (top left, left to right) to 7 (bottom left, left to right) and from 2 to 4 (top row, left to right). Pre- and posttreatment THCs were 279.0 μmol/L and 128.0 μmol/L, respectively. ΔTHCmean (tL) of the lesion was 54.1%. The first section (slice 1, top left) is a 6 × 6–cm spatial x-y image (coronal plane of the body) obtained at a depth of 0.5 cm, as measured from the skin surface. The last section (slice 7, bottom left) is a 6 × 6–cm spatial x-y image (coronal plane of the body) obtained at a depth of 3.5 cm towards the chest wall. Spacing between sections is 0.5 cm in the direction of propagation. The vertical color scale from blue to red is the THC in micromoles per liter from low to high.