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. 2017 Nov 20;11(11):e0006094. doi: 10.1371/journal.pntd.0006094

Table 1. Main characteristics of 43 patients with tegumentary leishmaniasis treated with liposomal amphotericin B.

Characteristics of patients n = 43
Demographics
Median age, years [range] 51 [1–86]
Male 29 (67)
Cardiovascular comorbidities and/or diabetes 7 (16)
Immunocompromised subject 5 (12)
Child 6 (14)
Clinical form
Localized cutaneous 32 (74)
Mucocutaneous 8 (19)
Disseminated cutaneous 2 (5)
Localized cutaneous with visceral involvement 1 (2)
Area where infection was acquired
Old World 28 (65)
New World 15 (35)
Leishmania Species (n = 35; 8 species unidentified)
L. braziliensis 11 (31)
L. braziliensis complex 2 (6)
L. guyanensis 1 (3)
L. amazonensis 1 (3)
L. infantum 9 (26)
L. major 6 (17)
L. tropica 3 (8)
L. donovani 2 (6)
Clinical findings
Number of lesions, median [range] 2 [1–30]
Larger lesion size (millimeter), median [range] 30 [4–200]
Treatment
Frontline therapy with L-AmB 30 (70)
Liposomal AmB cumulative dose (mg/kg), median [range] 20 [6–56]
Number of infusions, median [range]a 6 [2–14]
Outcome
Follow-up (days), median [range] 79 [28–803]
Complete healing without relapse 19 (44)
Improvement 2 (5)
Failure 17 (39)
Relapse 5 (12)
Adverse events
Patients with at least one adverse event 23 (53)
  Treatment modification due to adverse events 7 (16)

L-AmB, liposomal amphotericin B. Data are n (%) unless otherwise indicated.

a this information was available for 24 patients