Table 2. Analysis of changes in CK2 gene expression in CNS cancer.
Gene | p-value | Fold Change | Rank (Top %) | Dataset | #Samples | Reference |
---|---|---|---|---|---|---|
Astrocytoma | ||||||
CK2α | 0.001 | 1.352 | 8% | Shai Brain | 42 | [53] |
0.003 | -1.322 | 9% | Sun Brain | 180 | [58] | |
CK2β | 3.12 10−4 | 1.518 | 5% | Shai Brain | 42 | [53] |
Glioblastoma (Astrocytoma Grade IV) | ||||||
CK2α | 2.02 10−6 | 1.370 | 15% | Sun Brain | 180 | [58] |
2.33 10−4 | 1.294 | 11% | Shai Brain | 42 | [53] | |
9.21 10−4 | 4.072 | 13% | Bredel Brain 2 | 54 | [59] | |
0.01 | -2.382 | 42% | Lee Brain | 101 | [52] | |
CK2α’ | 2.59 10−4 | -2.132 | 23% | Lee Brain | 101 | [52] |
8.13 10−4 | -1.314 | 17% | Bredel Brain 2 | 54 | [59] | |
CK2β | 1.52 10−7 | 1.440 | 2% | Shai Brain | 42 | [53] |
1.19 10−5 | -2.338 | 14% | Lee Brain | 101 | [52] | |
Anaplastic Oligodendroglioma (grade III) | ||||||
CK2α’ | 1.15 10−6 | 1.637 | 3% | French Brain | 33 | [60] |
CK2β | 0.001 | 1.499 | 15% | French Brain | 33 | [60] |
Anaplastic Oligoastrocytoma (oligodendroglioma + astrocytoma) | ||||||
CK2α | 0.008 | 1.686 | 12% | French Brain | 33 | [60] |
CK2α’ | 0.004 | -1.624 | 14% | Bredel Brain 2 | 54 | [59] |
CK2β | 0.003 | 1.569 | 8% | French Brain | 33 | [60] |