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. 2017 Oct 2;207(4):1285–1299. doi: 10.1534/genetics.117.300347

Table 7. Numbers of significant SNPs (P-value <0.01).

CPMA LRT-Sum with Approach 2 (overlap) Wald-Sum with Approach 1 (overlap) Wald-Sum with Approach 2 (overlap)
With assumption 47 57 (46) 48 (47) 57 (46)
Without assumption 52 (43) 46 (45) 52 (43)

“With assumption”: assuming each SNP is already known to be significant for one trait, then testing whether there is at least one more significant association; “Without assumption”: directly testing whether there are at least two significant associations for each SNP; “Overlap”: the numbers of the significant SNPs that are also among the 47 detected ones by CPMA (“With assumption”).