Table 2. Attributes and features of the replicated MA sites with significant .
| CpG Site | Location | Methylation Change with Age | Nearest Gene | Genomic Features and States |
|---|---|---|---|---|
| cg02914422 | Chr 7: 32110145 | Age-methylated | PDE1C | CpG island |
| TFBS | ||||
| Polycomb repressed | ||||
| CTCF-binding site | ||||
| cg05691152 | Chr 22: 38092978 | Age-methylated | TRIOBP | TFBS |
| Weak/poised enhancer | ||||
| CTCF-binding site | ||||
| cg13672736 | Chr 9: 135114066 | Age-demethylated | NTNG2 | CpG shelf |
| Weakly transcribed | ||||
| cg25038330 | Chr 10: 463561 | Age-demethylated | DIP2C | CpG shelf |
| Hetrochromatin; low signal |
Chr, chromosome; TFBS, transcription factor-binding site.