Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Oct 18;7(12):3955–3966. doi: 10.1534/g3.117.300284

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2017 Mogre et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Kanamycin resistance of mutants. (A) Boxplots showing distributions of MICs of kanamycin of the wild type (WT) and various mutants. The number of replicates is mentioned over each boxplot. All mutants, except RpoD^L261Q, CpxA^F218Y, and CyaA^N600Y, are significantly more resistant than the wild type (Welch two sample t-test, P < 10⁻⁷). Although the medians of the FusA^A608E-RpoD^L261Q/CpxA^F218Y/TopA^S180L/CyaA^N600Y double mutants tend to be higher than that of the FusA^P610T mutant, this difference is not statistically significant (P > 0.09). The difference between the medians of these double mutants and the FusA^A608E mutant are statistically significant (P < 0.02), except in the case of the FusA^A608E-TopA^S180L mutant (P = 0.061) (B) Growth of mutants in 8-kan. (C) Growth of the RpoD^L261Q, CpxA^F218Y, and CyaA^N600Y mutants in 1.5-kan. In (B) and (C), error bars represent SD of eight replicates. Some part of this data had been generated in our previous work (Mogre et al. 2014), with the inclusion of more replicates and data of single mutants.