Skip to main content
. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Neuropharmacology. 2017 Nov 3;128:448–459. doi: 10.1016/j.neuropharm.2017.11.001

Table 2.

Summary of the negative results regarding the effects of adult-onset binge-drinking in GFP-infused controls, as well as the effects of intra-CEA H2-cDNA infusion upon our behavioral measures observed in early withdrawal. The data represent the means ± SEMs of the number of mice indicated in parentheses.

Test Dependent measure Water Alcohol
GFP (11) H2-cDNA (11) GFP (12) H2-cDNA (11)
Light-dark box Light-side entries 36.70 ± 2.84 29.36 ± 3.22# 32.42 ± 2.30 28.90 ± 2.83
Time spent on light side Fig. 6A
Latency to first light-side entry 37.07 ± 5.85 44.75 ± 8.63 34.34 ± 8.73 38.81 ± 4.86
Marble burying Marbles buried 1.18 ± 0.30 1.82 ± 0.72 1.55 ± 0.39 1.09 ± 0.34
Time spent burying Fig. 6B
Latency to begin burying 106.57 ± 21.44 70.28 ± 14.95 79.30 ± 16.15 94.48 ± 27.11
Forced swim test Immobile episodes 18.91 ± 2.52 12.18 ± 2.02# 15.17 ± 2.08 14.00 ± 2.73
Time spent immobile Fig. 6C
Latency to first immobility 72.85 ± 8.42 94.28 ± 9.88 67.33 ± 8.99 87.86 ± 8.24
#

p<0.10 vs. water-GFP.