Table 1.
Figures and Experimental Description | Summary of Results |
---|---|
Figure 1 Measurement of phasic DA combined with intraoral infusion (Section 2.4). |
I.o. infusion of 10% sucrose or 0.32% saccharin, but not 0.005% menthol nor water, increases phasic DA release in the NAc core. |
Figures 2–4 Combined i.o. and i.v. self-administration training and behavior using long training regimen (Section 2.5). |
Combined i.o. infusion of sucrose or saccharin with i.v. nicotine elevates self-administration compared to i.o. water or menthol combined with i.v. nicotine. Combined i.o. sucrose plus i.v. nicotine leads to decreased self-administration compared to i.v. nicotine alone. |
Figure 5 Progressive ratio test (Section 2.6) one day after long-training regimen. Rats used were the same as in Figures 2–4. |
No differences in sucrose, menthol, nor saccharin in breakpoint. |
Figure 6 Conditioned reinforcement test (Section 2.7) after receiving short training regimen (Section 2.5) |
Conditioned reinforcement for saccharin nor menthol were altered by nicotine pairings compared to saline pairings. |
Figure 7 Two-bottle choice (Section 2.8) |
Menthol or saccharin increase oral consumption of nicotine. |