Effects of MDL100907 (1.0, 2.0 mg/kg) pretreatment on TCB-2 (2.5 mg/kg)’s disruptive effect on pup retrieval. On PPD 4, the first VEH and MDL100907 was injected 10 min before the second VEH and TCB-2 injection. Pup retrieval was tested for 10 min at 30 min before (baseline), 30 min, 90 min and 150 min after TCB-2 injection. Number of pups retrieved in each test is expressed as mean + SEM. * p < 0.05, ** p < 0.01, *** p < 0.001 significantly different between the VEH+VEH and +TCB-2 groups. # p < 0.05 significantly different between MDL100907-(1.0 or 2.0)+TCB-2 and VEH+TCB-2 groups.