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Distal MCAO induced by 10 % FeCl3 and thrombolysis with tPA plus LB1 or vehicle treatment results. Systemic LB1 treatment plus tPA showed decreased infarct volume (A) along with hemorrhage area (B) at 4 hours after ischemia (p<0.05). LB1 administration also significantly reduced NSS compared to vehicle group (C). Weight loss in the treatment group was lower than in the vehicle group, but the difference was not statistically significant (D).
