Figure 3.
PSMB3 and PSMB5 were highly expressed in breast cancer cell lines compared to other cancer types. Identification of genomic PSMB family subunits copy number variation (CNV) and correlation with gene expression in Cancer Cell Line Encyclopedia. DNA copy number was measured using Affymetrix high-density single nucleotide polymorphism arrays (Affymetrix SNP 6.0), and the mRNA expression levels were obtained for each cell line using Affymetrix U133 plus 2.0 arrays. Plots showing PSMB subunits mRNA expression z-scores vs. copy number value from 967 cell lines that were obtained through the CCLE. Each dot represents one cell line, and color coded by different tumor type or subtype.