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GC exosomes induces CD25+CTLA4+FOXP3+ Treg cells Naïve T cells from healthy donors were cultured with rhTGF-β1 or GC patient-derived exosomes. After treatment, cells were stained and analyzed by flow cytometry. A. Representative density plot of FOXP3 expression in cultured cells. B. Quantitative analysis of CD25, CD45RA, FOXP3 and CTLA-4 expression in cultured cells. (*p<0.01 compared to control, †p<0.01 compare to TGF-β1, and ‡p<0.01 compare to exosome).
