Table 1.
Exosomal TGFβ-1 expression and clinicopatholgical correlation in 61 GC patients
| Factor | Case number | Expression of TGF-β1 in exosomes (pg/10^10 exosomes) | P-value |
|---|---|---|---|
| All patients | 61 | ||
| Age (years) | 0.27 | ||
| ≤60 | 29 | 14.1±2.6 | |
| >60 | 32 | 17.5±2.9 | |
| Gender | 0.57 | ||
| Female | 27 | 16.9±3.2 | |
| Male | 34 | 15.1±2.5 | |
| Tumor size (cm) | 0.29 | ||
| <3 | 27 | 13.7±2.3 | |
| ≥3 | 34 | 17.6±3.0 | |
| Location | 0.77 | ||
| Proximal+middle | 26 | 16.4±3.6 | |
| Distal | 35 | 15.5±2.2 | |
| Borrmann Type | 0.48 | ||
| I+II | 26 | 13.3±2.2 | |
| III+IV | 35 | 17.8±3.0 | |
| Differentiation | 0.33 | ||
| Well+Moderate | 40 | 16.7±2.6 | |
| Poor | 21 | 14.4±3.1 | |
| Lauren classification | 0.63 | ||
| Intestinal type | 23 | 18.4±3.7 | |
| Diffuse+Mixed type | 38 | 14.4±2.3 | |
| Tumor depth | 0.06 | ||
| T1+T2 | 22 | 12.7±2.7 | |
| T3+T4 | 39 | 17.7±2.7 | |
| Lymph node metastasis | 0.01 | ||
| No | 16 | 8.1±1.1 | |
| Yes | 45 | 18.7±2.5 | |
| Distant metastasis | 0.24 | ||
| No | 54 | 16.2±2.1 | |
| Yes | 7 | 13.4±6.6 | |
| TNM stage | 0.03 | ||
| I | 15 | 8.7±1.3 | |
| II+III+IV | 46 | 18.2±2.5 |