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Histological analysis of mice developing MOS-J tumors induced by intra-osseous injection. Longitudinal leg section with HE staining to assess degree of necrosis (A), IHC staining of tumor at × 5 magnification for proliferation with Ki67 (B), × 10 for vascularization with CD146 (C) and × 5 for apoptosis with caspase 3 (D). T: Tumor, N: areas of necrosis.
