Figure 4.

miR-24 targetes Bim mRNA3’UTR in hepatocytes. The data from targetscan reveals that Bim is a predicted target gene of miR-24 (A) The predicted binding sites of miR-24 targeting Bim mRNA3’UTR. pGL3-BIM-3’UTR (wt/mut) luciferase report plasmids were transfected with miR-24 inhibitor (B) or miR-24 mimic (C) While miR-24 non-specific inhibitor or non-specific mimic were transfected as control group. Data represent the mean value of three independent experiments. Mean ± SEM. **P<0.01, ***P<0.001 and N, P>0.05.