Table 2.
Trabecular and cortical microstructural parameters determined by μCT
| WT (mean ± SEM) | P2Y2R-Tg (mean ± SEM) | p value (n = 9–10) | |
|---|---|---|---|
| Trabecular bone | |||
| BMD (g/cm3) | 0.897 ± 0.004 | 0.898 ± 0.003 | 0.737 |
| BV/TV (%) | 20.7 ± 1.2 | 19.8 ± 0.5 | 0.512 |
| Tb.Th (mm) | 0.0592 ± 0.0005 | 0.0576 ± 0.0005 | 0.018 |
| Tb.N (1/mm) | 3.49 ± 0.20 | 3.44 ± 0.09 | 0.827 |
| Tb.Sp (mm) | 0.177 ± 0.008 | 0.170 ± 0.005 | 0.509 |
| Tb.Pf (1/mm) | 6.02 ± 1.59 | 9.38 ± 0.73 | 0.079 |
| SMI (−) | 1.23 ± 0.08 | 1.46 ± 0.05 | 0.027 |
| Cortical bone | |||
| BMD (g/cm3) | 1.234 ± 0.010 | 1.253 ± 0.009 | 0.180 |
| BV (mm3) | 4.51 ± 0.05 | 4.64 ± 0.07 | 0.166 |
| Porosity (−) | 1.02 ± 0.07 | 0.91 ± 0.05 | 0.246 |
| Ct.Th (mm) | 0.394 ± 0.006 | 0.406 ± 0.007 | 0.191 |
Statistically significant p-values are shown in bold.