Table 4.

Histomorphometry of the proximal tibia in P2Y2R-Tg and Wt rats

	WT (mean ± SEM)	P2Y2R-Tg (mean ± SEM)	p value (n)
ES/BS (%)	16.9 ± 0.5	18.9 ± 0.5	0.010 (9–10)
MS/BS (%)	60.6 ± 1.0	56.9 ± 0.5	0.008 (9–10)
MAR μm/day	0.94 ± 0.02	1.03 ± 0.03	0.032 (9–10)
BFR/BS (μm/day)	56.9 ± 1.5	58.6 ± 1.8	0.536 (8–10)
O.Th (μm)	11.0 ± 0.5	15.5 ± 0.6	< 0.001 (9–10)

Statistically significant p-values are shown in bold.

ES/BS eroded surfaces, MS/BS mineralized surfaces, MAR mineral apposition rate, BFR/BS bone formation rate, O.Th osteoid thickness