Table 4.
Distribution of drug resistant MTB isolates among Beijing and non-Beijing genotypes.
| Drug | No. of drug resistant isolates (%) | ||||||
|---|---|---|---|---|---|---|---|
| Beijing (n = 218) | Non-Beijing (n = 64) | P-value | Total (n = 282) | ||||
| Ancient (n = 67) | Modern (n = 151) | P-value | Total | ||||
| RIF | 22 (32.8) | 42 (27.8) | 0.45 | 64 (29.4) | 11 (17.2) | 0.05 | 75 (26.6) |
| INH | 46 (68.7) | 73 (48.3) | 0.01 | 119 (54.6) | 23 (35.9) | 0.01 | 142 (50.4) |
| SM | 34 (50.7) | 53 (35.1) | 0.03 | 87 (39.9) | 16 (25.0) | 0.03 | 103 (36.5) |
| EMB | 19 (28.4) | 33 (21.9) | 0.30 | 52 (23.9) | 7 (10.9) | 0.03 | 59 (20.9) |
| AMK | 4 (6.0) | 9 (6.0) | 1.00 | 13 (6.0) | 2 (3.1) | 0.37 | 15 (5.3) |
| LFX | 17 (25.4) | 25 (16.6) | 0.13 | 42 (19.3) | 9 (14.1) | 0.34 | 51 (18.1) |
| PTH | 12 (17.9) | 22 (14.9) | 0.53 | 34 (15.6) | 12 (18.8) | 0.55 | 46 (16.3) |
| MDR-TB | 22 (32.8) | 40 (26.5) | 0.34 | 62 (28.4) | 10 (15.6) | 0.04 | 72 (25.5) |
| XDR-TB | 3 (4.5) | 7 (4.6) | 1.00 | 10 (4.6) | 2 (3.1) | 1.00 | 12 (4.3) |
*RIF, rifampin; INH, isoniazid; SM, streptomycin; EMB, ethambutol; AMK, amikacin; LFX, levofloxacin; PTH, prothionamide; MDR-TB, multidrug resistant tuberculosis; XDR-TB, extensively drug resistant tuberculosis.