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. 2017 Nov 30;8:2358. doi: 10.3389/fmicb.2017.02358

Table 5.

Mutations in inhA, ethA, mshA, and ndh in 46 PTH-resistant MTB isolates.

No. of isolates (%) Resistance genotype
inhA promoter inhA ORF ethA mshA ndh
5 (10.9) WT WT S266R (AGC → AGG) WT WT
4 (8.7) −15C → T S94A WT WT WT
4 (8.7) −8T → C WT WT WT WT
4 (8.7) WT WT E36Q (GAA → CAA) WT WT
3 (6.5) −15C → T WT WT WT WT
2 (4.3) WT S94A WT WT WT
2 (4.3) −15C → T WT E36Q (GAA → CAA) WT WT
2 (4.3) WT WT S266R (AGC → AGG) WT WT
1 (2.2) WT WT W69R (TGG → CGG) WT WT
1 (2.2) WT WT R227P (CGC → CCC) WT WT
1 (2.2) −15C → T WT T314P (ACC → CCC) WT WT
1 (2.2) WT WT T392R (ACG → AGG) WT WT
1 (2.2) WT WT L301R (CTG → CGG) WT WT
1 (2.2) WT WT L374R (AAC → TAC) WT WT
1 (2.2) −15C → T WT WT N111S (AAC → AGC) WT
1 (2.2) WT WT WT N111S (AAC → AGC) S162T (AGC → ATC)
1 (2.2) WT WT WT WT L289R (CTT → CGT)
1 (2.2) −15C → T WT WT WT G339A (GGG → ATC)
1 (2.2) WT WT WT WT S388N (AGC → AAC)
9 (19.6) WT WT WT WT WT

ORF: open reading frame.