Table 6.
Common significant DE genes [FDR p-values (< 0.05), |Log2FC| >1] across treatments.
| Gene | Description | 33R vs. 38R | 33F vs. 38F | 43R vs. 38R | 43F vs. 38F | ||||
|---|---|---|---|---|---|---|---|---|---|
| Log2FC | FDR | Log2FC | FDR | Log2FC | FDR | Log2FC | FDR | ||
| ACTA1 | Actin, alpha 1, skeletal muscle | −3.205 | 2.2E-154 | −3.347 | 0 | −2.861 | 0 | −3.193 | 0 |
| APOA1 | Apolipoprotein A-I | −3.110 | 2.87E-36 | −3.113 | 1.19E-45 | −4.200 | 2.2E-53 | −2.404 | 1.29E-28 |
| BCAN | Brevican | −4.061 | 1.12E-67 | −3.839 | 1.93E-40 | −2.376 | 4.27E-27 | −2.095 | 9.01E-45 |
| C1QL1 | Complement component 1, q subcomponent-like 1 | −2.133 | 2.99E-40 | −2.465 | 4.61E-89 | −2.942 | 8.8E-80 | −2.162 | 1.15E-32 |
| CCDC69 | Coiled-coil domain containing 69 | −5.348 | 8.31E-17 | −4.015 | 9.4E-110 | −3.700 | 7.16E-11 | −2.138 | 3.22E-95 |
| CD36 | CD36 molecule (thrombospondin receptor) | 2.300 | 2.05E-46 | 2.479 | 9.79E-46 | −2.606 | 3.59E-17 | −2.131 | 3.52E-27 |
| DRC7 | Dynein regulatory complex subunit 7 | −4.210 | 2.88E-16 | −3.981 | 4.15E-24 | −2.259 | 7.2E-09 | −2.073 | 3.98E-12 |
| EVC | Ellis van Creveld syndrome | 3.026 | 0.005323 | 2.570 | 0.000106 | 3.119 | 0.000946 | 2.024 | 0.007842 |
| FABP3 | Fatty acid binding protein 3, muscle and heart | −5.284 | 7.79E-35 | −4.858 | 7.79E-41 | −3.020 | 1.97E-18 | −3.959 | 2.29E-36 |
| GUCA1B | Guanylate cyclase activator 1B (retina) | −3.228 | 2.28E-05 | −6.281 | 2.68E-05 | 2.990 | 1.44E-23 | 3.316 | 1.18E-25 |
| LNPEP | Leucyl/cystinyl aminopeptidase | 2.589 | 1.2E-07 | 2.319 | 4.07E-13 | 3.110 | 3.88E-16 | 2.267 | 1.53E-12 |
| LOC100539445 | Tensin-3 (TNS3) | 2.269 | 0.00123 | 2.321 | 6.04E-08 | 2.791 | 1.56E-09 | 3.026 | 9.17E-16 |
| LOC100545344 | Myosin-7-like | −4.975 | 2.4E-142 | −4.716 | 1.5E-45 | −2.988 | 8.58E-75 | −2.169 | 5.61E-42 |
| LOC100547876 | Polypeptide N-acetylgalactosaminyltransferase 12-like | 2.823 | 0.001667 | 2.930 | 9.26E-07 | 2.582 | 0.002754 | 2.215 | 0.001923 |
| LOC100548077 | Disheveled-associated activator of morphogenesis 2 (DAAM2) | 2.703 | 0.000521 | 2.031 | 0.009045 | 3.218 | 3.7E-06 | 2.329 | 0.000755 |
| LOC100548792 | Collagen alpha-1(XII) chain-like | 2.061 | 1.94E-06 | 2.720 | 2.64E-79 | 3.333 | 1.46E-33 | 2.652 | 4.26E-87 |
| LOC100549353 | Activating signal cointegrator 1 complex subunit 3 (ASCC3) | 2.127 | 3.37E-06 | 2.379 | 4.43E-16 | 2.699 | 1.16E-13 | 2.276 | 1.47E-16 |
| LOC100550192 | HLA class II histocompatibility antigen, DM beta chain-like (DMB2) | 2.263 | 0.003633 | 2.648 | 6.59E-05 | 3.586 | 4.06E-10 | 3.266 | 2.81E-09 |
| LOC104909264 | Multidrug resistance-associated protein 4-like | 2.217 | 5.61E-06 | 3.408 | 1.25E-16 | 2.207 | 1.27E-05 | 2.329 | 4.25E-06 |
| LOC104909289 | Limbin-like | 2.589 | 1.35E-06 | 3.524 | 3.22E-09 | 2.058 | 0.000628 | 2.740 | 0.000108 |
| LOC104909397 | Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (probable) | 2.464 | 0.002752 | 2.186 | 1.95E-06 | 3.644 | 1.56E-10 | 2.282 | 1.87E-07 |
| LOC104909635 | Latent-transforming growth factor beta-binding protein 1-like | 2.875 | 3.12E-11 | 3.039 | 2.66E-58 | 4.077 | 2.86E-66 | 3.716 | 3.9E-113 |
| LOC104909708 | Uncharacterized LOC104909708 (ncRNA) | −3.356 | 0.012361 | −3.268 | 0.000646 | −2.688 | 0.03465 | −3.090 | 0.000878 |
| LOC104909779 | Uncharacterized LOC104909779 (ncRNA) | 2.223 | 2.66E-05 | 2.640 | 7.28E-09 | 2.120 | 6.87E-05 | 2.361 | 2.74E-06 |
| LOC104909819 | Uncharacterized LOC104909819 (ncRNA) | −3.276 | 0.004612 | −4.031 | 0.000265 | −2.214 | 0.027631 | −2.483 | 0.005267 |
| LOC104909922 | Unconventional myosin-VI-like | 3.620 | 0.002294 | 4.227 | 1.24E-05 | 5.139 | 2.25E-08 | 4.453 | 1.39E-06 |
| LOC104909972 | Uncharacterized LOC104909972 (ncRNA) | 2.761 | 0.025565 | 3.318 | 7.03E-05 | 3.046 | 0.001915 | 2.946 | 0.002409 |
| LOC104910277 | Uncharacterized LOC104910277 (ncRNA) | 2.047 | 0.000265 | 2.011 | 8.08E-06 | 3.469 | 1.52E-14 | 3.345 | 6.5E-30 |
| LOC104910488 | Protein EFR3 homolog A-like | 2.207 | 0.001044 | 2.478 | 2.77E-08 | 3.242 | 1.65E-13 | 2.702 | 1.86E-11 |
| LOC104911116 | Tetraspanin-18-like | 2.542 | 1.11E-08 | 2.454 | 2.04E-16 | 3.174 | 1.45E-16 | 2.371 | 2.01E-15 |
| LOC104911697 | Lymphocyte antigen 75-like | 2.320 | 3.64E-06 | 2.737 | 2.24E-27 | 3.010 | 3.28E-17 | 2.467 | 1.3E-17 |
| LOC104912545 | Serine/threonine-protein kinase ATR-like | 2.556 | 0.008755 | 3.134 | 0.000424 | 2.518 | 0.004279 | 2.665 | 0.019456 |
| LOC104913390 | Multidrug resistance-associated protein 1-like | 3.731 | 2.77E-06 | 3.871 | 2.66E-12 | 3.832 | 1.01E-06 | 3.542 | 1.1E-09 |
| LOC104913470 | Periplakin-like | 6.430 | 2.91E-05 | 6.732 | 2.38E-07 | 6.104 | 0.000567 | 4.863 | 0.040654 |
| LOC104913553 | Uncharacterized LOC104913553 (ncRNA) | −2.071 | 7.56E-10 | −2.542 | 1.04E-24 | −2.187 | 8.27E-16 | −3.085 | 1.65E-42 |
| LOC104913838 | Uncharacterized LOC104913838 (ncRNA) | −6.959 | 4.68E-07 | −3.967 | 4.63E-07 | −2.318 | 0.000899 | −2.566 | 6.44E-05 |
| LOC104914081 | Regulator of G-protein signaling 9-binding protein-like | −3.633 | 1.72E-96 | −3.782 | 1.47E-36 | −4.970 | 1.7E-110 | −4.224 | 3.51E-39 |
| LOC104914095 | Probable phospholipid-transporting ATPase IIA | 3.083 | 0.02281 | 3.349 | 0.006467 | 3.225 | 0.018069 | 3.794 | 0.000706 |
| LOC104914454 | Importin-9-like | 2.093 | 2E-07 | 2.484 | 6.1E-18 | 2.003 | 1.92E-09 | 2.319 | 3.02E-15 |
| LOC104914932 | Protein LAP2-like | 2.253 | 1.33E-07 | 2.614 | 1.59E-18 | 2.978 | 1.19E-13 | 2.505 | 7.31E-17 |
| LOC104914983 | Rho guanine nucleotide exchange factor 28-like | 2.756 | 0.021236 | 2.875 | 0.032997 | 3.290 | 0.000905 | 4.226 | 2.95E-05 |
| LOC104915185 | Peptidyl-glycine alpha-amidating monooxygenase-like | 2.029 | 2.1E-13 | 2.194 | 1.66E-84 | 3.124 | 5.61E-93 | 2.504 | 3.61E-96 |
| LOC104915209 | Cyclin-G-associated kinase-like | 2.718 | 0.003993 | 2.098 | 0.002392 | 2.970 | 0.000509 | 2.078 | 0.002028 |
| LOC104915239 | Solute carrier family 12 member 2-like | 2.423 | 0.004607 | 4.386 | 1.2E-06 | 3.172 | 3.58E-07 | 4.979 | 8.76E-10 |
| LOC104915240 | Solute carrier family 12 member 2-like | 2.331 | 0.008301 | 3.373 | 4.27E-05 | 2.581 | 0.003403 | 3.312 | 0.000191 |
| LOC104915275 | Versican core protein-like | 2.117 | 3.28E-07 | 2.508 | 9.4E-19 | 4.283 | 6.06E-45 | 3.322 | 3.36E-41 |
| LOC104915303 | Structural maintenance of chromosomes protein 2-like | 2.372 | 1.45E-09 | 3.005 | 1.51E-47 | 3.395 | 5.32E-41 | 2.418 | 2.86E-19 |
| LOC104915418 | Uncharacterized LOC104915418 (ncRNA) | 2.830 | 0.014401 | 2.592 | 0.013781 | 3.176 | 0.000745 | 2.861 | 0.004775 |
| LOC104916051 | Uncharacterized LOC104916051 | 2.211 | 0.010683 | 4.739 | 1.72E-07 | 3.274 | 8.48E-08 | 5.184 | 2.35E-11 |
| LOC104916792 | Uncharacterized LOC104916792 (ncRNA) | 2.430 | 0.004417 | 2.450 | 0.000331 | 3.118 | 8.43E-06 | 2.330 | 0.000822 |
| LOC104916797 | Kinesin-like protein KIF20B | 5.546 | 0.012424 | 3.131 | 0.019325 | 5.632 | 0.003275 | 3.042 | 0.030237 |
| LOC104916915 | ETS translocation variant 3-like protein | 2.198 | 7.61E-05 | 2.887 | 1.53E-07 | 2.179 | 6.09E-05 | 2.863 | 1.6E-07 |
| LOC104916992 | Uncharacterized LOC104916992 (ncRNA) | −6.565 | 2.46E-78 | −6.353 | 4E-112 | −2.320 | 9.47E-22 | −2.022 | 2.86E-73 |
| LOC104917145 | Uncharacterized LOC104917145 (ncRNA) | 2.147 | 5.47E-05 | 2.680 | 2.39E-09 | 2.443 | 1.16E-06 | 2.382 | 1.55E-10 |
| LOC104917155 | Alpha-mannosidase 2-like | 3.184 | 8.61E-06 | 3.626 | 9.74E-23 | 4.006 | 1.55E-14 | 3.543 | 1.35E-21 |
| LOC104917232 | Alpha-mannosidase 2-like | 3.317 | 1.09E-05 | 3.119 | 3.95E-11 | 3.585 | 5.11E-08 | 2.802 | 1.73E-07 |
| LOC104917363 | Extended synaptotagmin-2-A-like | 2.174 | 0.01489 | 3.069 | 3.92E-12 | 2.452 | 0.000574 | 2.336 | 8.58E-05 |
| LOC104917414 | Uncharacterized LOC104917414 (ncRNA) | 3.090 | 2.57E-06 | 3.525 | 2.34E-09 | 2.547 | 0.000728 | 2.029 | 0.020654 |
| LOC104917580 | Sister chromatid cohesion protein PDS5 homolog B-like | 2.780 | 5.84E-05 | 2.052 | 2.19E-06 | 3.603 | 2.16E-11 | 2.307 | 2.47E-08 |
| MKI67 | Marker of proliferation Ki-67 | 2.867 | 6.91E-09 | 3.127 | 1.48E-31 | 4.181 | 6.74E-22 | 2.829 | 1.9E-24 |
| MSTN | Myostatin | −3.824 | 4.36E-08 | −2.382 | 1.94E-12 | −3.424 | 5.62E-07 | −2.480 | 5.71E-13 |
| MTMR8 | Myotubularin related protein 8 | 2.148 | 1.6E-07 | 2.456 | 1.51E-14 | 2.262 | 3.14E-10 | 2.143 | 3.91E-11 |
| MYL3 | Myosin, light chain 3, alkali; ventricular, skeletal, slow | −6.283 | 6.6E-130 | −7.377 | 0 | −3.687 | 3.26E-82 | −3.705 | 0 |
| PTGFRN | Prostaglandin F2 receptor inhibitor | 3.291 | 4.18E-06 | 2.740 | 1.19E-06 | 3.536 | 1.27E-07 | 3.300 | 3.07E-11 |
| REEP3 | Receptor accessory protein 3 | 2.363 | 5.13E-14 | 2.201 | 9.59E-31 | 2.646 | 6.37E-23 | 2.124 | 4.64E-30 |
| SLN | Sarcolipin | −5.226 | 1.34E-54 | −6.440 | 7.03E-80 | −3.335 | 2.34E-30 | −2.338 | 1.23E-38 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 2.357 | 1.73E-12 | 2.259 | 9.1E-12 | 3.078 | 1.95E-19 | 2.654 | 5.9E-32 |
| TNNC2 | Troponin C type 2 (fast) | −3.312 | 5.9E-126 | −3.349 | 0 | −4.650 | 7.4E-152 | −4.099 | 0 |
| TPM2 | Tropomyosin 2 (beta) | −2.732 | 1.51E-36 | −2.541 | 1.5E-107 | −2.289 | 1.47E-22 | −2.163 | 9.04E-96 |
| TSPAN10 | Tetraspanin 10 | −2.955 | 4.44E-18 | −2.432 | 3.11E-72 | −2.771 | 3.98E-16 | −3.485 | 3.72E-88 |
Comparisons highlighted red are up-regulated in the comparison whereas genes highlighted in green are down-regulated.