Table 1.
Parameters of field potential measurements after E-4031 treatment in CTSs with 50% cardiomyocytes (±s.d., n = 4)
| Beat rate (/min) | ISI (ms) | FPD (ms) | First peak amplitude (μV) | Conduction velocity (mm/s) | |
|---|---|---|---|---|---|
| 0 nM | 28 ± 12 | 2591 ± 1244 | 376 ± 172 | 498 ± 211 | 43 ± 24 |
| 0.3 nM | 27 ± 12 | 2656 ± 1265 | 384 ± 179 | 511 ± 211 | 44 ± 24 |
| 3 nM | 26 ± 14 | 2743 ± 1343 | 400 ± 183 | 524 ± 221 | 46 ± 22 |
| 10 nM | 28 ± 14 | 2609 ± 1284 | 422 ± 176 | 537 ± 217 | 46 ± 24 |
| 30 nM | 31 ± 14 | 2346 ± 1094 | 424 ± 152 | 541 ± 213 | 43 ± 26 |
| 100 nM | 29 ± 13 | 2412 ± 1078 | 482 ± 154 | 536 ± 210 | 48 ± 19 |
| 1 μM | N/A | N/A | N/A | 522 ± 218 | 42 ± 19 |
| 2 μM | N/A | N/A | N/A | 540 (n = 2) | 53 (n = 2) |
ISI interspike interval. N/A not available