Table 1.
Summary of the LifeGen parental lifespans
Ancestry | Parent | Count | Mean age | ||||
---|---|---|---|---|---|---|---|
Alive | Dead | Total | Alive | Dead | All | ||
African | Father | 2435 | 6924 | 9359 | 72.4 | 70.4 | 70.9 |
African | Mother | 4185 | 5889 | 10,074 | 73.1 | 70.7 | 71.7 |
European | Father | 113,611 | 178,017 | 291,628 | 62.9 | 71.2 | 68 |
European | Mother | 150,854 | 144,144 | 294,998 | 66.2 | 75.1 | 70.5 |
ALL | 271,085 | 334,974 | 606,059 |
Summary statistics for the 606,059 parental lifespans that passed phenotypic QC (in particular, parent age > 40) and were analysed here. In practice, fewer lives than these were analysed for some SNPs, as a SNP may not have passed QC in all cohorts (in particular within cohort MAF > 1%). The mean age of alive parents across European cohorts was reduced by the large iPSYCH cohort, of relatively younger subjects and thus parents, who were predominantly alive (mean father/mother age among the alive parents in iPSYCH was 52.4/50.4)