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. 2017 Dec 4;7:16883. doi: 10.1038/s41598-017-17113-7

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effects of acute inhibition of C1 neurons on MAP and HR in conscious control and CIH rats. (A) Representative recordings illustrating changes in baseline pulsatile arterial pressure [PAP], MAP and HR in response to Alst application into lateral ventricle of control and CIH rats transduced with PRSx8-AlstR-GFP-LVV and one control rat transduced with PRSx8-GFP-LVV into C1 region. Grouped data showing changes in MAP (Bi) and HR (Bii) 5 min after Alst application in control and CIH rats transduced with PRSx8-AlstR-GFP-LVV into C1 region.