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. 2017 Dec 4;7:16829. doi: 10.1038/s41598-017-16978-y

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Validation of 6 significantly upregulated (a) and 4 significantly downregulated (b) miRNAs as per microarray results in tumor vs normal adjacent tissues. These dotplots show the fold change of miRNA expression in 20 tumor breast tissues normalized to the average of 10 normal adjacent breast tissues with RNU6B used as an endogenous control. The plot represents the mean with the standard error of mean as error bars. *Denotes p < 0.05 for tumor versus normal adjacent tissues using Wilcoxon’s signed-rank sum test.