Table 1.
Clinical and pathological characteristics of Lebanese breast cancer tissues used in microarray and RT-qPCR.
| Patient Characteristics | Assay Type | |
|---|---|---|
| Microarray | RT-qPCR | |
| N(%) | N(%) | |
| Normal | 17 (27.4) | 10 (33.3) |
| Tumor | 45 (72.6) | 20 (66.7) |
| Age | ||
| ≤40 years | 19 (42.2) | 6 (30) |
| >40 years | 26 (57.8) | 14 (70) |
| Menopausal status | ||
| Premenopausal | 27 (60) | 10 (50) |
| Postmenopausal | 18 (40) | 10 (50) |
| ER status | ||
| Negative | 0 (0) | 0 (0) |
| Positive | 45 (100) | 20 (100) |
| PR status | ||
| Negative | 1 (2.2) | 0 (0) |
| Positive | 44 (97.8) | 20 (100) |
| HER2 overexpression | ||
| Negative | 34 (75.5) | 15 (75) |
| Positive | 11 (24.5) | 5 (25) |
| Lymph node involvement | ||
| No | 19 (45.2) | 9 (45) |
| Yes | 23 (54.8) | 11 (55) |
| Tumor size | ||
| T1: ≤2 cm | 19 (42.2) | 7 (35) |
| T2: >2 cm but ≤5 cm | 21 (46.7) | 10 (50) |
| T3: >5 cm | 4 (8.9) | 3 (15) |
| T4: any size with direct extension to chest wall and/or to skin | 1 (2.2) | 0 (0) |
| Tumor grade | ||
| G1: Well differentiated | 7 (15.6) | 2 (10) |
| G2: Moderately differentiated | 20 (44.4) | 12 (60) |
| G3–G4: Poorly differentiated | 18 (40) | 6 (30) |