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. 2017 Nov 30;8:651. doi: 10.3389/fneur.2017.00651

Table 1.

Characteristics of included studies.

Study characteristics Smith et al. (11) van Seeters et al. (13)
Study enrollment 2006–2009 2009–2013
Region United States, East and West Coast Netherlands
Recruitment sites 2 University hospitals 6 Universities, 8 non-University hospitals
Study type Prospective cohort Prospective cohort
Cerebral ischemia type AIS + TIA AIS
Sample size 643/675a 824
Age, mean (SD) 68.6 ± 15.3 67.7 ± 14.1
Sex, female 48% 41%
NIHSS, mean (SD) 7.63 (±7.29) 7 (3–13)b
Vessel imaging modality CTA CTA
Study entry time window <24 h of onset <9 h of onset
Time from onset to vessel imaging NR 118 min (median) (IQR 74–189)
Segments abstracted as large-vessel occlusions for this analysis Supraclinoid ICA, M1, M2, BA, intracranial VA Intracranial ICA, M1, P1, or BA
Timing of outcome modified Rankin scale assessment 180 days 90 days

AIS, Acute ischemic stroke; CTA, Computed tomography angiography; NR, not reported; ICA, internal carotid artery; MCA: middle cerebral artery; PCA, posterior cerebral artery; M1, first MCA segment; M2, second MCA segment; VA, vertebral artery; BA; basilar artery; IQR; inter-quartile range.

aStudy reported intracranial vessel imaging in 643/675 (95.2%) patients. Age, sex, and NIHSS data in this table are for the 675 patients; data in other tables are for the 643 with intracranial vessel imaging.

bStudy reported NIHSS as median (IQR), while mean (SD) was not reported.