Table 2.
Rates and outcomes of large-vessel occlusion (LVO) and non-LVO acute cerebral ischemia.
| Smith et al. (11) | van Seeters et al. (13) | Pooled model-adjusted estimates | |
|---|---|---|---|
| Study sample size | 643 | 824 | 1,467 |
| LVO, n (%) | 328 (51.0%) | 219 (26.5%) | 38.7% (CI: 21.8–55.7%) |
| Dependence and death (modified Rankin Scale 3–6) | |||
| Among all patients | 280/643 (43.5%) | 292/824 (35.4%) | 39.4% (CI: 33.7–45.0%) |
| Among LVO | 212/328 (64.6%) | 138/219 (63.0%) | 64.0% (CI: 60.0–68.0%) |
| Among non-LVO | 68/315 (21.6%) | 154/605 (25.5%) | 24.0% (CI: 21.3–26.8%) |
| Odds ratio (OR), LVO vs. non-LVO | 3.98 (2.86–5.54) | 4.99 (3.59–6.94) | 4.46 (CI: 3.53–5.63) |
| Fraction due to LVO | 212/280 (75.7%) | 138/292 (47.3%) | 61.6% (CI: 41.8–81.3%) |
| Mortality | |||
| Among all patients | 90/643 (14.0%) | N/A | 14.0% (CI: 11.4–16.9%) |
| Among LVO | 86/328 (26.2%) | N/A | 26.2% (CI: 21.5–31.3%) |
| Among non-LVO | 4/315 (1.3%) | N/A | 1.3% (CI: 0.3–3.2%) |
| OR, LVO vs. non-LVO | 4.09 (2.5–6.68) | N/A | 4.09 (2.5–6.68) |
| Fraction due to LVO | 86/90 (95.6%) | N/A | 95.6% (CI: 89.0–98.8%) |
N/A: not available.