Table 2.

Association between age, gender and white matter macrostructural measures.

		N	Mean (SD)	Age			Gender(female)
				B	SE	η2	B	SE	η2
CEREBRUM
Vol.	NAWM	200	462.318 (54.911)	−0.069**¶	0.010	0.109	−0.326**	0.121	0.016
	WMHa	196	2.399 (1.181; 4.456)	0.051**¶	0.014	0.059	0.388*	0.175	0.023
FRONTAL
Vol.	NAWM	199	193.720 (24.024)	−0.074**¶	0.010	0.127	−0.162	0.128	0.004
	WMHa	196	1.397 (0.670; 2.410)	0.045**¶	0.014	0.046	0.468**	0.177	0.033
PARIETAL
Vol.	NAWM	200	105.413 (13.149)	−0.049**¶	0.010	0.056	−0.439**¶	0.129	0.029
	WMHa	190	0.315 (0.123; 0.856)	0.053**¶	0.015	0.064	0.336	0.177	0.017
TEMPORAL
Vol.	NAWM	200	78.784 (9.632)	−0.074**¶	0.010	0.126	−0.428**¶	0.126	0.028
	WMHa	188	0.120 (0.043; 0.350)	0.024	0.015	0.012	0.302	0.180	0.014
OCCIPITAL
Vol.	NAWM	200	60.378 (8.383)	−0.055**¶	0.011	0.070	−0.426**	0.138	0.028
	WMHa	194	0.328 (0.158; 0.663)	0.022	0.015	0.011	−0.197	0.180	0.006

NAWM, normal appearing white matter; SD, standard deviation; SE, standard error; WMH, white matter hyperintensity; Vol., volume. Volumes for WMH and NAWM are indicated in ml.

^*p < 0.05;

^**p < 0.01;

^¶corrected for multiple comparisons.

All models were adjusted for education, diastolic blood pressure, and intracranial volume.

^anatural log transformed.