Table 6.

Effects between WM characteristics and processing speed performance.

		Cerebrum	Frontal	Parietal	Temporal	Occipital
NAWM Volumeb	B	0.213	0.147	0.203	0.219	0.114
	SE	0.103	0.099	0.097	0.100	0.092
	η2	0.020	0.010	0.020	0.022	0.007
	p	0.040	0.139	0.038	0.030	0.215
WMH Volumea,b	B	−0.096	−0.103	−0.058	−0.035	0.001
	SE	0.073	0.072	0.074	0.076	0.071
	η2	0.008	0.010	0.003	0.001	<0.001
	p	0.190	0.155	0.438	0.645	0.992
NAWM
FAc	B	0.068	0.075	0.002	0.044	0.015
	SE	0.074	0.075	0.075	0.071	0.071
	η2	0.004	0.005	<0.001	0.002	<0.001
	p	0.359	0.321	0.980	0.541	0.831
MDc	B	−0.169	−0.159	−0.175	−0.182	−0.098
	SE	0.084	0.086	0.079	0.079	0.079
	η2	0.020	0.017	0.024	0.026	0.008
	p	0.047	0.065	0.028	0.022	0.215
WMH
FAc	B	0.099	0.052	0.153	−0.011	0.036
	SE	0.069	0.072	0.070	0.080	0.070
	η2	0.010	0.003	0.023	<0.001	0.001
	p	0.152	0.473	0.030	0.896	0.610
MDc	B	−0.169	−0.092	−0.119	−0.037	−0.033
	SE	0.077	0.082	0.078	0.073	0.077
	η2	0.023	0.006	0.012	0.001	0.001
	p	0.029	0.266	0.128	0.618	0.667

FA, fractional anisotropy; MD, mean diffusivity; NAWM, normal appearing white matter; SE, standard error; WMH, white matter hyperintensity.

Significant results are indicated in bold, trends are indicated in italic.

^aNatural log transformed.

^bAdjusted for age, gender, education, blood pressure, and intracranial volume.

^cAdjusted for age, gender, education, blood pressure, intracranial volume, NAWM Volume, and WMH Volume.