Figure 4.

A) E ₅₀ values for the dissociation of all ligands by CAD of [RNA+m L−n H]ⁿ⁻ complex ions with n=2–5 versus the total number of ligands m (corresponding ligand structures with the guanidine moieties highlighted in black on top), B) E ₅₀ values for n=3 versus the number of atoms that can potentially be involved in hydrogen‐bond or salt‐bridge interactions with the RNA for m=1–5, C) E ₅₀ values at m=1 versus slope values E _slope from linear‐fit functions in (A) for n=2–4; the dashed lines indicate E ₅₀(m=1)/E _slope 1:1, 2:1, 3:1, and 4.4:1, D) E _slope versus complex net charge n (values at n=5 are shown in gray to highlight a systematic decrease in the values of E _slope).