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Possible RNA hairpin structure with A) one ligand bound to the phosphodiester/ribose moieties (shown as open circles) in the loop region and B) four additional ligands bound to the phosphodiester/ribose moieties of the stem. C) Truncated structure of the Gloeobacter violaceus guanidine II riboswitch P1 stem–loop with guanidine55 (pdb structure 5NEF).
