Table 3.
Brain regions | Nodal topology | r-value | p-value |
---|---|---|---|
Negative correlations between nodal topology with insomnia scores | |||
PoCG.R | BC | −0.455 | 0.011* |
PCUN.R | BC | −0.446 | 0.014 |
MTG.R | BC | −0.381 | 0.038 |
IOG.R | Deg | −0.382 | 0.038 |
PoCG.R | Deg | −0.466 | 0.010* |
SPG.R | Deg | −0.376 | 0.041 |
INS.L | Enodal | −0.524 | 0.003* |
SPG.L | Enodal | −0.393 | 0.032 |
Positive correlations between nodal topology with insomnia scores | |||
HES.L | BC | 0.461 | 0.010* |
INS.R | Deg | 0.503 | 0.005* |
HES.R | Enodal | 0.440 | 0.015 |
Pearson correlation analyses were corrected by controlling for age, gender, educational level, adjusted HAMA score and adjusted HAMD score. The AUC of the nodal topology was computed over the range of 0.1 ≤ S ≤ 0.2 with an interval of 0.01. R, right; L, left; AUC, area under the curve; BC, nodal betweenness centrality; Deg, nodal degree; Enodal, nodal efficiency; PoCG, postcentral gyrus; PCUN, precuneus gyrus; MTG, middle temporal gyrus; IOG, inferior occipital gyrus; INS, insula; SPG, superior parietal gyrus; HES, heschl gyrus; IS, healthy participants with insomnia symptoms. *Reported results are significant for p < 1/90 based on false positive correlation for multiple comparisons.