TABLE I.

Characteristics of the Study Cohort

Number of patients	66
Gender, n (%)
Male	40 (61)
Female	26 (39)
Age
>21 years, n (%)	31 (47)
≤21 years, n (%)	35 (53)
Mean ± SD (years)	23.1 ± 13.5
Median (range) (years)	19 (3–82)
Diagnosis, n (%)
Thalassemia major	38 (58)
Thalassemia intermedia	7 (11)
α-Thalassemia	1 (1.5)
Sickle cell disease	8 (12)
Diamond-Blackfan anemia	2 (3)
Leukemia	4 (6)
Other	6 (9)
Myocardial T2*, n (%)
≥20 ms	46 (70)
<20 ms	20 (30)
LV ejection fraction, n (%)
≥56%	57 (88)
<56%	8 (12)
MRI-derived HIC (mg/g dry weight)
Median (range)	9.1 (0.95–41.8)

HIC, hepatic iron concentration; LV, left ventricular; SD, standard deviation.