Table 2.
Comparison of pleural fluid LDH, ADA, and LDH/ADA ratio values between patients with TPE, UPPE, CPPE, and empyema
| Parameter | TPE [A] (n = 72) | UPPE [B] (n = 23) | CPPE [C] (n = 15) | Empyema [D] (n = 9) | P Values | ||
|---|---|---|---|---|---|---|---|
| A vs B | A vs C | A vs D | |||||
| Pleural LDH (U/L) | 364.5 (55–1154) | 316.8 (103–852) | 2275 (1012–4446) | 16,479 (1919–48,730) | .291 | < .0001 | < .0001 |
| Pleural ADA (U/L) | 33.5 (4.5–75.9) | 10.55 (2.0–26.1) | 37.9 (14.3–68.6) | 137.9 (31.5–344.1) | < .0001 | .377 | < .0001 |
| Pleural LDH/ADA ratio | 10.88 (3.65–21.81) | 41.33 (9.04–162.4) | 67.3 (41.96–260.9) | 87.50 (15.11–411.4) | < .0001 | < .0001 | < .0001 |
Values are medians (range)
ADA, adenosine deaminase; CPPE, complicated parapneumonic effusions; LDH, lactate dehydrogenase; PPE, parapneumonic pleural effusion; TPE, tuberculous pleural effusion UPPE; uncomplicated parapneumonic effusion