Table 2.
Renal replacement therapy delivery parameters in non-tunneled versus tunneled dialysis catheters used for AKI requiring renal replacement therapy
| Adjusted analysesb | |||
|---|---|---|---|
| RRT Delivery Parameter | NTDC (n = 140)a | TDC (n = 80)a | p-value |
| CVVH | |||
| Blood flow ml/min, mean ± SE | 242.8 ± 4.9 | 246.3 ± 6.2 | 0.44 |
| Median venous access pressure, mean ± SE | 87.9 ± 7.4 | 121.1 ± 9.7 | <0.001 |
| Median arterial access pressure, mean ± SE | 58.3 ± 6.4 | 80.3 ± 8.2 | <0.001 |
| Hours of CVVH, mean ± SE | 17.8 ± 1.2 | 17.9 ± 1.5 | 0.91 |
| BUN, mean ± SE | 59.8 ± 9.5 | 58.6 ± 11.0 | 0.86 |
| Rate Ratio of interruptions per catheterc | 2.7 (1.7–4.3) | 1 (ref) | <0.001 |
| IHD | |||
| Blood flow ml/min, mean ± SE | 319.0 ± 12.8 | 368.2 ± 13.0 | <0.001 |
| Median venous pressure, mean ± SE | 84.6 ± 8.9 | 145.1 ± 9.1 | <0.001 |
| Median arterial pressure, mean ± SE | 108.3 ± 10.5 | 179.3 ± 10.7 | <0.001 |
BUN Blood urea nitrogen; CVVH Continuous veno-venous hemofiltration; IHD Intermittent hemodialysis; NTDC Non-tunneled dialysis catheter; RRT Renal replacement therapy; SE Standard error; TDC Tunneled dialysis catheter
aNumber of catheters
bAdjusted for ATN risk score, history of chronic kidney disease, renal team and AKI cause (ATN vs others)
cFrom mixed effect models