Figure 1.

Ex vivo inhibition of PLY‐induced swelling by MgCl₂. (A) Relative density (lower density indicates higher water content and swelling) of brain slices after 6 h incubation without treatment (mock), with exposure to 4 HU·mL⁻¹ PLY, treatment with 2 mM Mg only (Mg) or combined exposure to PLY and Mg (n = 6 independent experiments). (B) Concentration‐dependent inhibition by Mg²⁺ of rat brain swelling after 6 h co‐exposure of 4 HU·mL⁻¹ PLY (n = 5 independent experiments). (C) Effect of 2 mM Mg to 4 HU·mL⁻¹ PLY on penetration of dextran‐TRITC in rat brain slices (n = 5 independent experiments). *P<0.05, significantly different as indicated.