Table 1.
Definition of abnormal blood test results for the 28 included blood tests
| Blood test interval | Reference group | Definition of abnormal result | |
|---|---|---|---|
| Inflammation | |||
| CRP | High | All | ≥8.0 mg/l |
| ESR | High | Men under 50 years old Men 50 years or older Women under 50 years old Women 50 years or older |
≥ 15 mm/h ≥ 20 mm/h ≥ 20 mm/h ≥ 30 mm/h |
| Immunology | |||
| IgA | Low | All | < 0.8 g/l |
| High | Under 50 years old 50 years or older |
> 3.90 g/l > 4.90 g/l |
|
| IgG | Low | All men, and women 50 years or older Women under 50 years old |
< 6.1 g/l < 6.9 g/l |
| High | All men, and women 50 years or older Women under 50 years old |
> 14.9 g/l l > 15.7 g/l |
|
| IgM | Low | All men, and women 50 years or older Women under 50 years old |
< 0.39 g/l < 0.55 g/l |
| High | All men, and women 50 years or older Women under 50 years old |
> 2.08 g/l > 2.30 g/l |
|
| Haematology | |||
| White blood cell count | Low | All | < 3.5 × 109/l |
| High | All | > 10.0 × 109/l | |
| Neutrophil count | Low | All | < 2.0 × 109/l |
| High | All | > 7.0 × 109/l | |
| Eosinophil count | High | All | ≥ 0.5 × 109/l |
| Basophil count | High | All | ≥ 0.10 × 109/l |
| Metamyelocyte count | High | All | ≥ 0.05 × 109/l |
| Monocyte count | Low | All | < 0.2 × 109/l |
| High | All | > 0.7 × 109/l | |
| Lymphocyte count | Low | All | < 1.3 × 109/l |
| High | All | > 3.5 × 109/l | |
| Platelet count | Low | Men Women |
< 145 × 109/l < 165 × 109/l |
| High | Men Women |
> 350 × 109/l > 400 × 109/l |
|
| Anaemia | |||
| Haemoglobin | Low | Men Women |
< 8.3 mmol/l < 7.3 mmol/l |
| Liver and metabolism | |||
| Albumine | Low | Under 70 years old 70 years or older |
< 36 g/l < 34 g/l |
| Alkaline phosphatase | High | All | > 105 U/l |
| ALK | High | Men Women |
> 70 U/l > 45 U/l |
| Bilirubin | High | All | > 25 μmol/l |
| Amylase | High | All | > 120 U/l |
| Calcium total | High | All | > 2.55 mmol/l |
| LDH | High | Under 70 years old 70 years or older |
>205 U/l >255 U/l |
| Uric acid | High | Men Women under 50 years old Women 50 years or older |
>0.48 mmol/l >0.35 mmol/l >0.40 mmol/l |
| Tumour markers | |||
| M protein | High | All | ≥ 2.0 g/l |
| sFLC ratio | Low | All | < 0.26 |
| High | All | > 1.65 | |
| AFP | High | All | ≥ 7 KU/l |
| PSA | High | Men under 60 years old Men between 60 and 69 years old Men 70 years or older |
≥ 3.0 μg/l ≥ 4.0 μg/l ≥ 5.0 μg/l |
| hCG | High | Men | ≥ 2 IU/l |
| CA-125 | High | Women | ≥ 35 kIU/l |
The blood tests were divided into intervals according to the reference range used at the Department of Clinical Chemistry at Silkeborg Regional Hospital
Abbreviations: CRP C-reactive protein, ESR erythrocyte sedimentation rate, IgA immunoglobulin A, IgG immunoglobulin G, IgM immunoglobulin M, ALT alanine aminotransaminase, LDH lactate dehydrogenase. sFLC serum-free light chain κ/λ ratio, AFP alpha-fetoprotein, PSA prostate-specific antigen, hCG human chorionic gonadotropin, CA-125 cancer antigen 125